Do not freeze. This is an amazing drug as statins could not get my LDL as low as it is. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. In one study (OSLER-1), volunteers on Repatha lowered their "bad" LDL cholesterol from 140 to 61 mg/dl ( Journal of the American College of Cardiology, Oct. 29. Please share your positive and negative experiences with the drug, and compare it with other treatments you have used. Continue reading. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Because they're water-soluble, you can take them with or without food and at any time of the day. -For patients receiving 420 mg once a month, LDL-C should be measured just prior to next scheduled dose. Fatigue is also a problem now. You can find a list of inactive ingredients in the Repatha Patient Information or you can ask your pharmacist for a copy. Follow any state or local laws about throwing away used needles and syringes. Funny pain with tooth implant I never had before; dentist cannot find reason for inflamed area. I have been having shooting pain down both my arms my shoulders I get bad cramps in one leg I didnt put two into together thinking that maybe I hurt myself or maybe my mattress is no good thats why my shoulders are aching now after the fourth dose Ive been having diarrhea kind of a clay color not normal usually thats liver issues havent had my second blood test since Ive only taken four doses but I dont think I want to take this medication anymore. You should aim to take biotin at the same time each day to stay on track. By the evening of the 6th I went to the hospital fearing I was having a stroke.. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The Pushtronex on-body infusor is a special hands-free device placed on the skin that needs around 9 minutes to slowly deliver a full dose of Repatha. Repatha Cautionary Labels Uses of Repatha Repatha is a prescription medication used: Selenium is excreted in the stomach within 24 hours. This WAS the perfect solution for my genetic hyperlipidemia. It works for me and others been on it for nearly 7 months.. Ask your doctor or pharmacist if you have any questions about your injection device, or call the manufacturer at 1-844-737-2842. The drug lowered my LDL cholesterol to around 60. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum (updated 25 Oct 2022), ASHP (updated 12 Oct 2022) and others. Hoping to get my life back, but understand it may take months. Day and half later had disabling dizziness, abdominal cramps and diarrhea. Why do you need to take Repatha (evolocumab) long term? I had struggled with high cholesterol all my life and had to get off Statins due to side effects. But then I started to get sever muscle cramps in my calves at night. ago At night so I'm sleeping during the initial side effects Double_dash44 5 mo. o If you or your child have HoFH, the recommended starting dose is 420 mg once monthly. Typical dosing for Repatha (evolocumab) Repatha (evolocumab) is injected under the skin in your stomach, thigh, or upper arm. It's driving me nuts. In your description, mention the brand, dose, and period of time that you used the drug or treatment. Adult patients with primary hyperlipidemia, including heterozygous familial hypercholesterolemia (HeFH) take Repatha alone or in addition to change in diet or with other LDL-C lowering medications to lower LDL-C. The 2-pack carton costs roughly $507. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Repatha only for the indication prescribed. Depending on your dose amount, you may need to use up to 3 separate injections at one time. Initial dose: 420 mg subcutaneously once a month Well worth the mild pain if that's even the cause. implant/ normal X- ray., never taking again; dizziness too scary and disabling. Started taking repatha in may 2020. Can cause uti. Only possible side effect that started when I began Repatha is a cramp like pain on left side of abdomen. 8 months.Cholesterol and All lipids Way down from extremely High - to Low Normal Now including CRP, Which was Very high( inflammation in my body,! The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you have any questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Use a different place each time you give an injection. Do not include any personal information or links in your review. My blood pressure kept getting worse, Repatha also caused what went from a stuffy nose (treated with Flonase and Afrin) to water blisters inside my nasal passages. Repatha Information for Healthcare Professionals, swelling of the face, lips, tongue, throat or arms, symptoms of the common cold, like a runny nose or sore throat (nasopharyngitis), upper respiratory tract (lung) infections, redness, pain, or bruising at the injection site. Do not inject Repatha into skin that is bruised, sore, scarred, or hardened. Copyright 1996-2022 Cerner Multum, Inc. I developed unusual weak feeling in large muscles, like hypoglycemia. After using Repatha for the past 6 weeks and having had three 140mg injections I began suffering Chronic Fatigue, Lethargy, brain fog/inattention and lower back pain to the extent that I cannot function. Repatha is available as an injection. Fantastic results. Last updated on Sep 29, 2021. I still have problems but not as bad. This has been great for me. The drug could have triggered an autoimmune reaction, like statins do. My total cholesterol and LDL have dropped dramatically. Low-density lipoprotein (LDL) is considered "bad" because it can build up on the walls of the arteries . Patients 10 years or older who have HeFH take Repatha in addition to change in diet and with other LDL-C lowering medications to lower LDL-C. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Other than that, it works as well as the Praluent my insurance required me to switch from. -Patients on lipid apheresis may initiate treatment with 420 mg subcutaneously every 2 weeks to correspond with their apheresis schedule; administer after apheresis session is complete. Started Repatha in November 2021, some minor aches. Follow your doctor's instructions very closely. I had no idea what was wrong with me over the last 4-5 months. My Blood pressure has also increased though not dangerous yet. But. Repatha reduces the level of low-density lipoprotein cholesterol (LDL-C). -For patients receiving 420 mg once a month, LDL-C should be measured just prior to next scheduled dose. The drug was very effective in lowering LDL, too effective I guess. Also tell your doctor if you are allergic to rubber or latex. Throw away after one use, even if there is still some medicine left inside. My doctor started me on repatha as my numbers are really bad. I was also able to get the $5 monthly co-pay from Repatha's website. Your doctor will prescribe either a 140-mg. Also tell your doctor if you or your child are breastfeeding or plan to breastfeed. It is NOT the type of medicine that can fix a health issue after a short treatment course. Skip the missed dose if you are more than 7 days late for the injection. I have been taking 2 doses a month for 3 1/2 months. What are the new treatment options for migraines? Then came burning bladder, nausea, lightheadedness, difficulty concentrating, nightmares, fatigue, diarrhea. More won't help you sleep better, but it might cause stomach upsets. You can inject Repatha at any time of the day, but usually people prefer injecting Repatha during daylight hours because it takes 30 to 45 minutes for it to warm up to room temperature, and you need to be able to easily see what you are doing while you are injecting it. Other drugs may interact with evolocumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Grateful! Talk to a RepathaReady Nurse I believe my joints are damaged for life. Stopped Repatha 11 months ago and since then had endless investigations. I am 64 years old - weigh 155 and have no other underlying health conditions. Continue reading, The cost for Repatha (evolocumab) subcutaneous solution (140 mg/mL) is about $258.00 for one of the 140 mg single-use prefilled autoinjectors or a prefilled syringe. Literally a life saver. 3rd injection in had a massive allergic reaction with throat tightening, not able to swallow, rash on my throat massive mucus attacks and also reflux. Dosing every 2 weeks is easy. Learn how we can help. I studied the copious information sheets and nowhere do they mention chronic fatigue. Different pharmacy: Ferrous sulfate should be available from a different pharmacy. Posted on . I am now 54 days off repatha and am having allergic reactions as above to foods and medications I've been eating and taking forever. Decided to try it again 2 weeks ago. Repatha can also be stored at room temperature (68F to 77F) in its original box for up to 30 days. The amount of selenium in the body is best in the morning and at night. I do not recommend this drug unless it is a 'last resort'. -For patients receiving 420 mg once a month, LDL-C should be measured just prior to next scheduled dose. The cardiologist did not discuss side effects with me when he prescribed the drug. Last updated on Dec 16, 2021. Do not inject into the same place two times in a row. Does anyone know if I can do that? I agree with others that more studies need to be performed. A cardiologist was finally able to get my insurance to pay for Repatha for my familial hypercholesterolemia (I have a genetic mutation in my LDL receptor gene). Its a 10/10 for me. Adult patients who have established cardiovascular disease take Repatha long term to reduce their risk of future cardiovascular events. Should biotin be taken at night? Im done with it!! Im completely fatigued. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. I have anxiety over starting any medicine as I have a fast processing liver and a genetic liver enzyme that makes it difficult for me. Kind Regards, Kay. Hopefully I will feel better after a month. Finally they were so severe it felt like I would have them at any moment all day or night, including my right inner thigh. We comply with the HONcode standard for trustworthy health information. I am on sure click 140 mgs every two weeks. Drug information contained herein may be time sensitive. My legs, feet and hands cramp to the point I cant sleep. Continue reading, Instructions on how to inject Repatha using Repatha prefilled syringe, Repatha SureClik Autoinjector, and the Pushtronex system (Repatha on-body infusor) for Repatha. Concomitant Use with Lipid Apheresis: The most common side effects of Repatha include: symptoms of the common cold, like a runny nose or sore throat (nasopharyngitis) flu or flu-like symptoms upper respiratory tract (lung) infections back pain high blood sugar levels (diabetes) redness, pain, or bruising at the injection site To see a detailed list of Repatha side effects visit here. My doctor advised me to skip the next dose as the MRI did not show any cause for my stomach pain. Call your pharmacist for new medicine. For now it is only industry paid studies only. After a missed dose, go back to your original schedule and use the medicine again when your next scheduled dose is due. Repatha is used together with a low-fat diet and other cholesterol-lowering medications in people with homozygous or heterozygous familial hypercholesterolemia (inherited types of high cholesterol). Repatha one (1) month free trial offer is limited to one-time one month supply and may only be used once per patient per lifetime. If It makes you feel bad.don't take it! Follow your doctor's dosing instructions very carefully. WOrks very well for me. Stopped it and slowly felt better. Dr. Gurmukh Singh answered. Comments: Many people ask themselves when is the right time to take biotin. There is not enough data what these new drugs, monoclonal antibodies can do. What is the best time of day to take Repatha? Use: As an adjunct to diet and other LDL-C-lowering therapies in pediatric patients 10 years or older with HeFH, to reduce LDL-C. Use the missed dose within 7 days after that injection was due. Stopped taking this biologic. This drug should be off the market or at least have a "black box" warning. A serious danger of taking Repatha (evolocumab) includes a possibly life-threatening allergic reaction. I am a physician and took Repatha for 10 months. Im 50 years old male, had very high cholesterol for 20 years, tried every anti cholesterol tablets with horrible side effects but repatha reduced my cholesterol by half within a month and very little side effects! I failed all the statins and one other drugs due to bad muscle aches. I am at 28 days from the last dose and feel significantly better. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. I finally read the side effects of all my medications and couldn't believe what I read about Repatha . Get everything you need ready: your Repatha SureClick Autoinjector, alcohol wipe, cotton ball and sharps disposal container. I've been on Repatha for 6 months. I inject every 2 weeks. Initially had flu-like symptoms for 4 days. Ive gained 17 lbs in 6 months all belly fat. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum (updated 25 Oct 2022), ASHP (updated 12 Oct 2022) and others.

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